Columbia University Dissertations: Dissertations

Biological Sciences: Dissertations

2007 - 2006 - 2005 - 2004 - 2003 - 2002 - 2001 - 2000 - 1999 - 1998 - 1997 - 1995

2007 DISSERTATIONS

Foat, Barrett C. (2007) Quantitative modeling of gene expression regulation by RNA-binding proteins and transcription factors in Saccharomyces cerevisiae

Kaneko, Shuzo (2007) Functional studies of mRNA 3'-end formation and transcription termination

Karni-Schmidt, Orit (2007) Nucleolar localization properties of the p53 protein

Lokshin, Maria (2007) Differential activity and regulation of family members p53 and p73

Mattia, Melissa C. (2007) Examining the role of p53 in transcription, target gene selection and cell cycle regulation

Melillo, Jessica Ann (2007) Tissue specific deletion reveals stat3 as a critical regulator of dendritic cell activity

Nobile, Clarissa Jane (2007) Genetics and genomics of Candida albicans biofilm formation : identification of a new adherence regulatory pathway

Savitsky, David A. (2007) Blimp-1 in B-1 B lymphocytes, macrophages and multiple myeloma

Smelkinson, Margery G. (2007) Regulation of the hedgehog signaling effector cubitus interruptus by slimb dependent partial proteolysis and control of specific activity

Weisstaub, Noelia V. (2007) Cortical 5-HT2A receptor signaling and its role in anxiety and the action of hallucinogenic drugs

Zornik, Erik J. (2007) Regulating breathing and calling in an aquatic frog : neuronal networks in the Xenopus laevis hindbrain

Zupnick, Andrew E. (2007) Regulation of p53's tumor suppressive functions

2006 DISSERTATIONS

Avila, Frank William (2006) The JAK/STAT pathway in Drosophila sex determination

C̣okol, Murat (2006) Features of distributed thinking in biomedical communities

Meshi, Dar Barry (2006) The effects of environmental enrichment on behavior

Shen, Yang (2006) Structural and mechanistic studies on the biotin carboxylase and the carboxyltransferase of acetyl-coenzyme a carboxylase

Steinhauer, Josefa (2006) Screen for enhancers of PKA in Drosophila oogenesis : the RNA binding protein squid is required for anterior-posterior polarity

Tao, Xiao (2006) Structural and functional studies on human DJ-1 (PARK7), a protein associated with early-onset Parkinson's disease

Zhang, Xiang (2006) Predictive identification of cis splicing signals in the human transcriptome

Zirin, Jonathan D. (2006) Pattern formation along the proximal-distal axis of the Drosophila wing

2005 DISSERTATIONS

Chesler, Alexander (2005) Identity and development of olfactory neurons

Jiang, Guoying (2005) Studies of Talin 1 and RPTPα in cellular force generation and extracellular matrix rigidity sensing

Karpowich, Nathan (2005) Structural and biochemical characterization of ATP binding cassettes from ABC transporters

Kuhn, Jeanette (2005) Studies of molecular aspects of development in the medicinal leech (Hirudo medicinalis) : actin isoforms, mRNA localization and signaling

Leung, Sandra Wan-Ping (2005) Manipulating neuroendocrine tumorigenesis in Rb+/-Mice u sing E2f1-deficiency and genetic backgroung

Li, Xiaofan (2005) Functional studies of PAK4 and PAK5, two members of group B p21-activated-kinases

O'Hagan, Robert (2005) Components of a mechanotransduction complex in C. elegans touch receptor neurons : an in vivo electrophysiological study

Poyurovsky, Masha (2005) Biochemical and molecular studies of the Mdm2 RING domain

Xie, Cheng (2005) Functional architecture and location of the activation gate of voltage-gated calcium channels

2004 DISSERTATIONS

Baptiste, Nicole (2004) Transcription-dependent and transcription-independent functions of p53 in apoptosis

Kohn, Matthew (2004) In vivo analysis of Dp1 function during mouse development

McKinney, Kristine (2004) Deconstructing the mechanism of p53 DNA binding

Moon, Woongjoon (2004) Gens required for germ cell development and patterning in Drosophila oogenesis

Selvaraj, Ahalya (2004) Functional characterization of the MKL family of SRF co-activators and identification of their target genes

Shen, Jingshi (2004) ER stress activation of ATF6 by selctive transport to the Golgi and intramembrane proteolysis

Shin, Chanseok (2004) Functional studies of the SR protein SRp38 as a general splicing repressor

Urist, Marshall (2004) Checkpoint kinases in p53 family signaling

Wang, Lu-yong (2004) Covariation analysis in recurrent local structures and local structure prediction

Wu, Li (2004) Dual regulation of voltage-gated calcium channels by phosphatidylinositol 4.5-bisphosphate

Zhang, Shifang (2004) Stomatin gene family in Caenorhabditis elegans

2003 DISSERTATIONS

Cammarano, Marta (2003) RhoGTPase signaling pathways in cell growth regulation and transformation

Chen, Zheng (2003) Functional analysis of a transcriptional cofactor, TAF9, in vertebrate cells

Khayat, Reza (2003) Biophysical studies of the human cytomegalovirus protease

Mansfield, Jennifer (2003) The role of a cytoplasmic RNP particle in patterning the Drosophila egg

Valadkhan, Saba (2003) Catalytic and folding properties of protein-free spliceosomal snRNSs

Yang, Zhiru (2003) Structural and biochemical studies on malic enzymes

Zhang, Xinmin (2003) Genomics of olfactory receptors and vomeronasal receptors

Zheng, Ye (2003) The role of NF-[Kappa]B in mature T lymphocyte function and apoptosis

2002 DISSERTATIONS

Dan, Chuntao (2002) Regulation of acting cytoskeleton and neuronal morphogenesis by P21-activated kinases

Tashiro, Ayumu (2002) Rapid motility of dendritic spines and axonal filopodia

Tsiola, Areti (2002) Quantitative morphological classification of layer 5 neurons from mouse primary visual cortex

Wu, Ji (2002) Restriction of touch cell fate by egl-44 and egl-46 in C. elegans

Zhang, Yun (2002) Identification of genes needed for the differentiation of Caenorhabditis elegans touch receptor neurons

Zhou, Jianmin (2002) Transcription-independent functions of p53 in DNA replication/repair processes

2001 DISSERTATIONS

Bond, Gareth (2001) Poly(A) polymerase, the cell cycle and cell death

Cain, Christine (2001) The regulation of p53 DNA binding

Chen, Xi (2001) The regulation of ATF6 in the endoplasmic reticulum stress response

Dutt, Anindita (2001) Cloning of leech enabled (Lena) : a putative binding partner of HmLAR

Edwards Christofer (2001) Vocal production and recognition in Xenopus laevis

Fairbrother, William (2001) Human genomic sequences that inhibit splicing

Ivic, Lidija (2001) Signaling in vertebrate olfactory receptor neurons

Jin, Can (2001) Characterization of pleiotropic pet mutants defective in regulation of mitochondrial respiration and mitochondrial protein synthesis

Qu, Jian (2001) Cloning, characterization, and gene-targeting of PAK4 : a novel kinase regulating cytoskeletal reorganization and oncogenic transformation

Zhang, Tingting (2001) The post-translational regulation of MDM2 : stability and phosphorylation

Zhang, Yan (2001) Cell proliferation and pattern formation in Drosophila oogenesis

2000 DISSERTATIONS

Ansari, Husamuddin (2000) A novel role for cyclophilin A as a regulator of nuclear transport

Otaki, Joji Matsumoto (2000) Functional expression of an odorant receptor, molecular cloning of neurestin, and length analyses of G-protein-coupled receptors

Shen, Baohe (2000) Signal transduction of Toll pathway in the Dorsal-Ventral polarity of Drosophila embryos

Sun, Hanzhen (2000) Multiple splicing defects in an intronic false exon

Thornton, JOseph (2000) The evolution of molecular novelty : mechanisms for generating and selecting new proteins and functions in the nuclear receptor superfamily

Um, Moonkyoung (2000) Studies on functions of TATA-binding protein in vivo

Wang, Yan (2000) ThesisPR

Yang, Dun (2000) Sex determination and RNAi in Drosophila

Zabetakis, Dan (2000) Studies on NSR1

1999 DISSERTATIONS

Cong, Feng (1999) Signal transduction mediated by Abl Tyrosine kinase

Euskirchen, Ghia (1999) Genetic identification of four essential spindle pole body proteins in yeast

Hendrickson, Mary (1999) Cell cycle regulation of the MCM complex in initiation of DNA replication

Kanki, Hiroaki (1999) Functional analysis of FAP-1 and promoter analysis of its gene

Torres, Martha (1999) Factors contributing to ribosomal RNA transcription antitermination in escherichia coli

Van Eyndhoven, Winfried (1999) Genomic and functional analysis of TRAF-3

Voulgaris, Justina (1999) Studies of ribosomal RNA synthesis in Escherichia coli

Xue, Yingzi (1999) Functional analysis of Notch signaling in mice

1998 DISSERTATIONS

Cash, Sydney (1998) Neuronal structure and function : effects of axonal and dendritic morphology on signal propagation and integration in vertebrate neurons

Du, Hongping (1998) Development and function of the touch receptor neurons in Caenorhabditis elegans

Duggan, Anne (1998) Studies of neural development in Caenorhabditis elegans

Evans, Ben Jonathan (1998) Hybridization, molecular phylogeography, and population structure : case studies of clawed frogs and macaque monkeys

Gu, Guoqiang (1998) A molecular model for mechanosensory transduction in Caenorhabditis elegans

Li, Chi (1998) Mechanism and regulation of the transcriptional repressor even-skipped

Ohlmeyer, Johanna (1998) The roles of PKA, fused and suppressor of fused in the hedgehog signal pathway in Drosophila melanogaster

Wang, Jin (1998) Genetic analysis of SR protein ASF/SF2

Wang, Shengxian (1998) Role of the Drosophila exuperantia gene in the localization of bicoid mRNA during oogenesis

Zhao, Wenqing (1998) Biochemical and genetic studies of poly(A) polymerase

1997 DISSERTATIONS

Bhattacharyya, Subarna (1997) Regulation of the function of polyoma virus large T antigen in initiation of ori-DNA replication in vitro

Cohen, Michael Adam (1997) The androgen receptor, a multifunctional transcription factor with roles in masculinization and in embryonic development

Colgan, Dianna Foukal (1997) Poly(A) polymerase activity is repressed during M-phase via phosphorylation of its C-terminal regulatory domain by MPF

Friedlander, Philip Adam (1997) Biochemical and functional analysis of wild-type and mutant p53 proteins

Gershon, Timothy Robin (1997) The role of the receptor tyrosine phosphatases HmLAR1 and HmLAR2 in process outgrowth during development in leeches

Hayward, Michael Dennis (1997) Proto-oncogne involvement in progrqmmed cell

Jayaraman, Lata (1997) Regulation of the DNA binding function of the tumor-suppressor Protein p53

Miller, Scott David (1997) Interaction of p53 with elements of the DNA replication/repair process

Mintzer, Keith A. (1997) Assembly of a Ras responsive adenylyl cyclase complex

O'Donnell Johnson, Amy (1997) Molecular signals involved in the specialized trafficking of membrane proteins through the endocytic pathway

Paresce, Donata Maria (1997) Uptake and metabolism of the Alzheimer's disease amyloid -protein by microglia Donata Maria Paresce.

Sun, Jing-Song (1997) Genetic and biochemical studies of the interactions between U2, U6 snRNAs and Pre-mRNA in mammalian Pre-mRNA splicing

Wong, Victoria Yat Sum (1997) Characterization of homeobox genes expressed in the leech CNS

Yan, Catherine Theresa (1997) Insights into nuclear structure and function in yeast as revealed by the analysis of the nuclear-associated interactions of the nucleolar protein, Nsr1p, and the actin-related protein, Act2p

1995 DISSERTATIONS

García Añoveros, Jaime (1995) Genetic analysis of degenerin proteins in Caenorhabditis elegans

Huang, Mingxia (1995) Mechanosensory genes in Caenorhabditis elegans

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